Gamma Knife Radiosurgery for Intraventricular Meningioma: A Single Institute Experience

Park, Sang Man; Kim, Min Soo; Jung, Na Young; Park, Chang Kyu; Chang, Won Seok; Chang, Jin Woo; Park, Yong Gou; Jung, Hyun Ho

Original article

Journal of the Korean Society of Stereotactic and Functional Neurosurgery 2016;12(2):53-57.
Published online September 30, 2016.

Gamma Knife Radiosurgery for Intraventricular Meningioma: A Single Institute Experience

Sang Man Park, Min Soo Kim, Na Young Jung, Chang Kyu Park, Won Seok Chang, Jin Woo Chang, Yong Gou Park, Hyun Ho Jung

Department of Neurosurgery, Yonsei Gamma Knife Center, Yonsei University College of Medicine, Seoul, Korea

Abstract

Objective
To evaluate the outcome and complications following gamma knife radiosurgery (GKS) for rare intraventricular meningiomas.
Methods
Between May 1992 and December 2015, 15 patients with intraventricular meningiomas were treated with GKS as the primary modality among 6398 cases of GKS for meningioma in our institute. The mean age was 49 years (range, 36-61 years). One patient was excluded due to a short follow-up period; thus, 14 patients were included. The mean tumor volume was 4.54cc (range, 0.95–18.1cc) and the mean follow-up was 62.1 months (range, 11.9–144.5 months). The mean maximal dose was 20.4Gy (range, 18.4–22.8Gy) and the mean marginal dose was 10.2Gy.
Results
An overall tumor control rate was 93% (13/14) for more than 12 months. The tumor volume was stable in six cases (43%) from 12 to 136 months, and had regressed in 7 cases (50%) from 58 to 144 months. Seven patients (50%) experienced subjective side effects such as headache, memory impairment, and tingling sensation on the face. Peritumoral edema (PTE) following GKS was noted in 9 patients (64%), with new onset of PTE after GKS in 7 cases and aggravated of PTE in 2.
Conclusion
While tumor control after GKS for intraventricular meningioma does not appear to be different from that for other locations of meningioma, the occurrence of PTE appears to be high. Furthermore, inspecting tumor volume before GKS may provide information regarding the likelihood of PTE following GKS.

Key Words: Intraventricular meningioma, Gamma knife radiosurgery, Peritumoral edema.