The Short-Term Relief of Cancer Pain Around Perineum by Ganglion Impar Block |
Min-Soo Kim, Tae-Kyu Lee, Sei-Yun Yang, Tae-Yeon Won, Sang-Bok Lee, Do-Sung Yoo, Pil-Woo Huh, Kyung-Souk Cho |
Department of Neurosurgery, Uijeongbu St Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea |
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Abstract |
Purpose To demonstrate the effect of the ganglion impar block (GIB) for relief of perineal pain caused by cancer in pelvic cavity
Methods and Materials: Since January 2010, 14 patients with cancer pain around perineum were treated by GIB. These patients complained vague, burning and sharp perineal pain unresponsive to medication with opioid. GIB under fluoroscopy was
performed. Pain intensity was measured using a visual analogue score (VAS) and daily morphine consumption was measured at
baseline and follow up visits after GIB.
Results In all patients, pain relief [VAS 4.79±1.63 (mean±SD)] had been achieved after GIB and lasted for 4 weeks (3.14±
0.86 after 1 day : 2.71±0.83 after 1 week : 3.00±0.88 after 2 weeks : 3.29±0.83 after 3 weeks : 5.21±1.63 after 4 weeks).
The maximum reduction by 70.0% from the baseline VAS score observed after two weeks (p=0.001) and pain relief is statistically significant during follow-up visits for 4 weeks (p=0.001). Regarding the daily morphine consumption, the baseline was
96.00±32.60 mg/day, which significantly reduced to 66.00±20.00 mg/day after the first 1day post procedure (p=0.001). Daily
morphine consumption was reduced to a maximum by 67.34% up to 1 week after GIB compared to the baseline. Complications during GIB did not occur in this study.
Conclusion A GIB is an effective and safe technique for relief of cancer pain around perineum. GIB is not curative , nonetheless appear to have meaningful palliative effects for a short period. |
Key Words:
Cancer pain, Ganglion impar block. |
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