Long-term Follow-up Results of Gamma Knife Radiosurgery for Vestibular Schwannoma??More than 5-years?? Experience |
In Yook Lyo, Yang Kwon, Doo Hee Lee, Soon Young Kim, Hyun Go Kwon, Chang Jin Kim, Byung Duk Kwun, Jung Kyo Lee |
Department of Neurological Surgery, Asan Medical Center, University of Ulsan, Seoul, Korea |
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Abstract |
Object: The goal of this study was to define tumor control and complications of radiosurgery encountered using current treatment methods for vestibular schwannoma.
Methods Eighty patients with vestibular schwannomas underwent gamma knife radiosurgery between 1990 and 1998. The mean marginal tumor dose varied from 13.5Gy (range 12-17Gy). The mean isocenters used per patient was 6.7 (range 1-12). Mean tumor volume was 6900mm3 (range 126-28380). Mean follow-up periods were.
Results The actuarial 5-year clinical tumor-control rate (no requirement for surgical intervention) for the entire series was 93.8%. Five-year actuarial rates for any new facial weakness, facial numbness, hearing loss rates were 2.5%, 0.02%, and 50%, respectively.
Conclusions Radiosurgery for vestibular schwannoma performed using current procedures is associated with a high rate of tumor control and lower rates of morbidity after GKRS. |
Key Words:
Radiosurgery, Vestibular schwannoma. |
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